Wednesday, January 1, 2014

Can At your Stem Cells Regenerate Normal cartilage?

Lay media consentrate on stem cell (SC) therapy has generally committed to two areas:

1. The declaration of embryonic SC
2. The proliferation of charlatans preying at the dreams and fears of several helpless patients.

While embryonic SC, in theory, appear to potentially be the best option for tissue regeneration, the hype has exceeded the hope. Because of political and ethical concerns, research efforts with one of these cells has been depressing.

At the same work, news articles and television commentaries actually have dealt with controversial aspects of SC therapy. An inordinate amount of time has been devoted to pick exposing the seamy facet... individuals involved in completely hucksterism, the possible breach of SC therapy on the part of practitioners, as well your implication that all SC research conducted outside informative centers is suspect.

As a result, there has been neglect regarding on the fascinating and promising have any effect, particularly in Arthritis Treatment.

One by more intriguing studies was recently published by Korean investigators (Pak T. Regeneration of human bones in hip Osteonecrosis and human cartilage in elbow OsteoArthritis with autologous adipose-derived peel cells: a case rendition. J Med Case Recommendations. 2011; 7: 296)

The Korean physicians treated four smoking quality. Two (a 29 year old woman and a 47 year old man) had Osteonecrosis to your personal hip. Two other patients (a 70 year old woman and a 79 year old man) had OsteoArthritis to your personal knee. They were all given a mix of autologous stem cells (the patient's own stem cells) derived from fat along with platelet abundant plasma, hyaluronic acid, nanogram amounts of dexamethasone, and calcium chloride.

Pre and post Treatment MRI scans were within all subjects. In honest of patients with Osteonecrosis, a revolutionary bone formation was historical. In the patients the back OsteoArthritis, new cartilage production was seen.

Along by having an MRI findings, both subjective pain measures and wanted outcomes improved.

I found these findings along the lines of extremely interesting for a number of reasons.

First, the mixture used via Korean report is similar to the one that the revolutionary use at our fundamental, with one exception. The exception can this be: In addition to pick a SC, we also start using bone marrow derived establish cells.

And, while our center has had excellent results with knee OsteoArthritis (more than 90 p'cent success), our experience with both hip OsteoArthritis and complete hip Osteonecrosis has been recently disappointing.

Why the difference between hip and knee? I suspect it's because the mechanical forces vary. The anatomy of your own hip joint allows extreme rotation instead of the knee joint which is especially a hinge joint with many rotation and some leading. Activity level and body weight are contributing factors.

Nonetheless, this report from Korea underscores what we believe to be true... the use of autologous establish cells, also known while much repair stem cells, will prove to be a fruitful area of the progress in OsteoArthritis research for end.


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